How to set URL alias of node when using Pathauto module

You can use the following code to set URL alias for a node if your website also uses Pathauto

 $node->path = [

      'alias' => '/' . $node_url,
      'pathauto' => Drupal\pathauto\PathautoState::SKIP,

];
    $node->save();

Where $node_url is the desired alias and $node is loaded node object.